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Cell Culture HeLa cells were obtained from the Lerner Research Institute of the Cleveland Clinic Foundation (Cleveland, OH)

Sigma 1 receptor as a therapeutic target for amyotrophic lateral sclerosis

As a tumor suppressor, YY2 negatively regulates de novo serine synthesis by binding to the PHGDH promoter and repressing its transcriptional activity, thereby inhibiting tumorigenesis (104)

Prolonged use of glucocorticoids can lead to more serious complications, such as osteoporosis and adrenal suppression, necessitating careful management and potential adjunct therapies to mitigate these risks